Pharmacist developed & tested ENDOMAL-SP KIT
Tablet

ENDOMAL-SP KIT

Endomal-SP Kit is a combination antimalarial treatment pack containing Artesunate, Sulphadoxine and Pyrimethamine. It is formulated for the treatment of malaria caused by susceptible Plasmodium parasites.

3 tablets of Artesunate 200mg + 2 tablets of Sulphadoxine 750mg + Pyrimethamine 37.5mg
Anti-malarial
Tablet
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Medicine Information

Product information:

Endomal-SP Kit is a combination antimalarial treatment pack containing Artesunate, Sulphadoxine and Pyrimethamine.

It is formulated for the treatment of malaria caused by susceptible Plasmodium parasites, with the combination providing complementary antimalarial activity to help clear parasites from the bloodstream.

Key Benefits:

  • Artesunate generates free radicals, damaging parasite membranes causing rapid kill of Plasmodium falciparum.
  • Sulfadoxine blocks dihydropteroate synthase (DHPS) which prevents folate synthesis and halts parasite DNA replication.
  • Pyrimethamine inhibits dihydrofolate reductase (DHFR) and stops conversion of folic acid thereby preventing parasite growth.
  • Artesunate ensures fast onset, Sulfadoxine + Pyrimethamine provide sustained suppression ensuring complete clearance and resistance prevention.
  • Combination therapy improves cure rates even in drug‑resistant strains.
  • Recognized globally as Artemisinin‑based Combination Therapy for malaria management.
  • Rapid fever reduction, prevention of relapse, and reduced mortality.

Directions for use:

Use Endomal-SP Kit only as prescribed by a qualified healthcare professional. Take the tablets exactly according to the prescribed schedule and in the recommended sequence. Swallow the tablets with water; they may be taken with or after food unless otherwise advised.

Complete the full prescribed course even if symptoms improve. Do not alter the dose, skip doses, or repeat treatment without medical advice. Do not use this kit for self-treatment of undiagnosed fever.

Storage and Safety Information:

  • Store in a cool, dry place, protected from direct sunlight and moisture.
  • Keep the kit in its original packaging and out of reach of children.
  • Use only under the supervision of a qualified healthcare professional.
  • Inform your doctor about any known allergy to sulphonamide medicines or other medicines, and about any liver, kidney, or blood-related disorders.
  • Sulphadoxine/pyrimethamine can rarely cause serious skin or blood-related reactions. Seek immediate medical attention if severe rash, blistering, mouth sores, unusual bruising, or persistent sore throat develops.
  • Seek medical attention if fever persists, symptoms worsen, or malaria symptoms recur.
  • Use during pregnancy or breastfeeding only on the advice of a qualified healthcare professional.

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