Pharmacist developed & tested ENDOMAL-L
Tablet

ENDOMAL-L

Endomal-L Tablet is a fixed-dose antimalarial combination containing Artemether 80 mg and Lumefantrine 480 mg. It is used for the treatment of uncomplicated malaria caused by susceptible Plasmodium falciparum parasites.

Arte-mether 80mg + Lumefantrine 480mg
Anti-malarial
Tablet
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Medicine Information

Product information:

Endomal-L Tablet is a fixed-dose antimalarial combination containing Artemether 80 mg and Lumefantrine 480 mg. It is used for the treatment of uncomplicated malaria caused by susceptible Plasmodium falciparum parasites.

The combination provides antimalarial activity through complementary mechanisms, helping eliminate malaria parasites from the bloodstream.

Key Benefits:

  • Artemether generates free radicals that damage parasite membranes causing rapid kill of Plasmodium falciparum.
  • Lumefantrine inhibits heme polymerization causing toxic heme accumulation and parasite death.
  • Artemether ensures quick onset, Lumefantrine ensures complete clearance which prevents relapse and resistance.
  • Combination therapy improves cure rates even in drug‑resistant strains.
  • Recognized globally as part of Artemisinin‑based Combination Therapy for malaria management.
  • Rapid fever reduction, reduced parasite load, and lower recurrence risk.
  • Easy administration with fixed‑dose combination providing better patient compliance.

Directions for use:

Take Endomal-L Tablet exactly as prescribed by a qualified healthcare professional. Take the tablet with food or a drink containing fat, as this helps improve absorption of lumefantrine. Swallow the tablet with water; do not crush or chew unless specifically advised. Complete the full prescribed treatment course, even if you start feeling better.

If vomiting occurs shortly after taking a dose, consult your healthcare professional regarding whether the dose should be repeated. Do not self-medicate or alter the dosage without medical advice.

Storage and Safety Information:

  • Store in a cool, dry place, protected from direct sunlight and moisture.
  • Keep the medicine in its original packaging and out of reach of children.
  • Use only under the supervision of a qualified healthcare professional.
  • Inform your doctor about any history of heart rhythm problems, liver disease, or other significant medical conditions.
  • Inform your healthcare professional about all medicines, including other antimalarial medicines, you are taking, as some medicines may interact with Artemether/Lumefantrine.
  • Seek medical attention if malaria symptoms worsen, recur, or do not improve during treatment.
  • Use during pregnancy or breastfeeding only after consultation with a qualified healthcare professional.

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