Pharmacist developed & tested ALGAMET
Tablet

ALGAMET

Algamet Tablet is a combination of Nortriptyline and Pregabalin, formulated for the management of neuropathic (nerve-related) pain. The combination may be prescribed for conditions associated with burning, tingling, shooting or electric-shock-like nerve pain, as directed by a healthcare professional.

Nortriptyline 10mg + Pregabalin 75mg
Anti-neuropathic agent
Tablet
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Medicine Information

Product information:

Algamet Tablet is a combination of Nortriptyline and Pregabalin, formulated for the management of neuropathic (nerve-related) pain. The combination may be prescribed for conditions associated with burning, tingling, shooting or electric-shock-like nerve pain, as directed by a healthcare professional.

Pregabalin helps reduce abnormal nerve signals involved in pain, while Nortriptyline, a tricyclic antidepressant, helps modulate pain signalling pathways.

Key Benefits:

  • Nortriptyline modulates central pain pathways, while Pregabalin stabilizes peripheral nerve activity providing comprehensive neuropathic pain control.
  • Effective in diabetic neuropathy, post‑herpetic neuralgia, and chronic nerve pain.
  • Nortriptyline enhances serotonin & norepinephrine balance ensuring better emotional well‑being and sleep quality.
  • Pregabalin reduces calcium influx at nerve terminals, decreasing abnormal excitatory signaling.
  • Early reduction in burning, tingling, and shooting pain sensations.
  • Well‑tolerated combination with minimal sedation and dizziness compared to monotherapy.
  • Trusted regimen for chronic neuropathic conditions requiring dual (central & peripheral) action.

Directions for use:

Take Algamet Tablet exactly as prescribed by your physician. Swallow the tablet whole with water; do not crush or chew unless advised otherwise. It may be taken with or without food, preferably at the same time each day.

Do not stop treatment suddenly, particularly after prolonged use. Your physician may gradually reduce the dose when discontinuing treatment.

Storage and Safety Information:

  • Store in a cool, dry place, away from direct sunlight and moisture.
  • Keep out of reach of children.
  • Common adverse effects may include drowsiness, dizziness, blurred vision, dry mouth, constipation, fatigue or difficulty concentrating.
  • Inform your doctor if you have kidney disease, heart rhythm problems, glaucoma, urinary retention, or a history of seizures.
  • Pregabalin may cause dizziness and drowsiness and may impair coordination; exercise caution while driving or operating machinery.
  • Do not discontinue Pregabalin abruptly without medical advice, as withdrawal symptoms may occur.
  • Inform your doctor about all medicines and supplements you are taking, particularly sedatives, sleeping medicines or other medicines affecting the nervous system.
  • Seek immediate medical attention if you develop facial or throat swelling, difficulty breathing, severe allergic reactions, unusual mood changes or thoughts of self-harm.
  • Use during pregnancy or breastfeeding only on medical advice.

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